These tails are topic to a number of post-translational covalent modifications, together with acetylation, phosphorylation, ubiquitination, sumoylation and methylation (reviewed in 1 ). Methylation been found on a range of lysine residues in varied histones: K4 (using the only-letter amino-acid code for lysine), K9, solicitor news K27, K36 and K79 in histone H3, K20 lawyers in my area histone H4, K59 within the globular area of histone H4 2 and K26 of histone H1B three Several proteins accountable for the methylation of specific residues have been characterized, and all however one in all these comprises a SET domain